Precise Synthesis Based on Tetracoordinate Boron Intermediates

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Instructors/Speakers

Prof. Qiuling Song
College of Materials Science and Engineering Huaqiao University

Zoom No.: 97895805410, Password: 072087

Abstract

Organoboron compounds are a class of multifunctional reagents for the construction of carbon-carbon and carbon-heteroatom bonds in modern synthetic chemistry. The transformation of organoboron compounds is usually carried out through tetracoordinate boron intermediates, mainly including additions to unsaturated bonds, rearrangements, transmetallations and so on. Although great progress has been achieved on tetracoordinate boron species, there are still shortcomings such as sparse activation modes, paucity of reaction strategies and difficulties on stereoselective control. In the past several years, we have focused on the development of unconventional transformations of organoboron compounds based upon the design of tetracoordinate boron intermediates, including the following three aspects: 1) the construction of C-B bonds; 2) the construction of C-C bonds; 3) the construction of chiral C-H bonds.

Biography

Prof. Song received a B.S. degree from Zhengzhou University (1998), M.S. degree from Peking University (2001) working with Professor Zhenfeng Xi, and Ph.D. at Princeton University (2006) working with Professor Robert Pascal. After conducting industrial pharmaceutical research for several years, she joined the faculty in the College of Materials Science at Huaqiao University in 2012. Prof. Song’s research interests range from organoboron and organofluorine chemistry to free-radical chemistry with an emphasis on the synthesis of biologically active organic molecules following green chemistry approaches. She has published over 170 papers with H-index 36. She serves as an Associate Editor of the Journal of Heterocyclic Chemistry and Green Synthesis & Catalysis and on the Editorial Board of Chinese Chemical Letters and Chinese Journal of Pharmaceuticals. Among her awards and honors, Prof. Song was selected as Fellow of The Royal Society Chemistry (2021), and awarded Theme Chemistry Journal Award (2021), several Asian Core Program Lectureship Awards (2018 and 2019), the Quanzhou Natural Science First Prize (2017), and received the 6th China Overseas Chinese Contribution Award (2016) and the Fujian Province Hundred Talents Program (2013).

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